CONOLIDINE ALKALOID FOR CHRONIC PAIN SECRETS

Most recently, it has been discovered that conolidine and the above derivatives act around the atypical chemokine receptor three (ACKR3. Expressed in similar places as classical opioid receptors, it binds to some big range of endogenous opioids. As opposed to most opioid receptors, this receptor acts to be a scavenger and does not activate a 2nd me